What do a comic genius and an internationally renowned psychiatrist have in common? Quite a bit, it turns out. So much, in fact, that Harper’s Magazine and Book Culture on Columbus brought John Cleese and Iain McGilchrist together for two nights of conversation. On the first night, McGilchrist, author of The Master and His Emissary, interviewed Cleese; on the second, Cleese, author of Professor at Large, interviewed McGilchrist. With wit and intelligence, the two men delved into the philosophical and biological underpinnings of how we each understand the world.