An estimated one out of every four Nigerians is a silent carrier of sickle cell disease, a hemoglobin disorder that can cause serious health problems and even death. With recent advancements in genetic testing, many Nigerians won’t take the risk of reproducing with other silent carriers or people with the disease. But, as Krithika Varagur reports, love doesn’t always accord with the Punnett square. Providing a snapshot of what our “genetic responsibility” could be as prenatal tests proliferate, Varagur sat down with Harper’s Magazine senior editor Elena Saavedra Buckley to discuss one couple’s story of public health, family, and most of all love in Lagos.

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